A special serum für the mesoporation treatment of skin in need of regeneration with a visible improvement of the skin texture. Low-molecular hyaluronic acid saturates the skin and stores moisture over a longer period of time. The skin appears plumped up and is given a youthful look. The extract of plant stem cells protects the skin and strengthens the natural resistance of the skin against environmental stress factors. The growth of new cells is stimulated and the lifespan of the skin stem cells is prolonged, so that the youthfulness of the skin lasts longer.